[Nucleus translocation in migrating neurons: key control by Sema6A and plexin A2].
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منابع مشابه
Npgrj_nn_2064 440..449
During their migration, cerebellar granule cells switch from a tangential to a radial mode of migration. We have previously demonstrated that this involves the transmembrane semaphorin Sema6A. We show here that plexin-A2 is the receptor that controls Sema6A function in migrating granule cells. In plexin-A2–deficient (Plxna2 –/–) mice, which were generated by homologous recombination, many granu...
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The cardiac neural crest, a subpopulation of the neural crest, contributes to the cardiac outflow tract formation during development. However, how it follows the defined long-range migratory pathway remains unclear. We show here that the migrating cardiac neural crest cells (NCCs) express Plexin-A2, Plexin-D1 and Neuropilin. The membrane-bound ligands for Plexin-A2, Semaphorin (Sema)6A and Sema...
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ورودعنوان ژورنال:
- Medecine sciences : M/S
دوره 24 10 شماره
صفحات -
تاریخ انتشار 2008